KCa3.1/KCa2.3 potassium channels as target structures in cerebro-cardiovascular disease, metabolic syndrome, organ fibrosis. “Proof-of-Concept-Trials”.

Publicado en:

1. Hasenau AL, Nielsen G, Morisseau C, Hammock BD, Wulff H, Köhler R. Improvement of endothelium-dependent vasodilations by SKA-31 and SKA-20, activators of small- and intermediate-conductance Ca2+-activated K+-channels. Acta Physiol (Oxf) 203(1):117-26, 2011.

2. Schmidt K, Dubrovska G, Nielsen G, Fesüs G, Uhrenholt TR, Hansen PH, Gudermann T, Dietrich A, Gollasch M, de Wit C, Köhler R. Amplification of EDHF-type vasodilatations in TRPC1-deficient mice. Brit J Pharmacol 161(8):1722-33, 2010.

Author: 
Köhler , Ralf
Principal researcher: 
Ralf Köhler
Scope: 
Internacional
Entidades participantes: 
Unversidad Aarhus y SDU, Dinamarca; Universidad de California Davis, U.S:A
Number of researchers: 
3
Start date: 
01/2009
End date: 
01/2012
Entidad financiadora
Financing entity: 
Deutsche Forschungsgemeinschaft y Novo Nordiskfonden